Tegafur drug page Clinical trials

Trials with Tegafur

Every colorectal cancer trial that includes this drug. Those looking for patients come first.

6Trials
0Recruiting
5Countries
3.439Planned patients

Showing 1–6 of 6

Erbitux Study of CPT11, Oxaliplatin, UFToral Targeted Therapy
Finished Phase 2 47 patients NCT01225744

A Phase II trial to demonstrate the response rate, using the Response evaluation criteria in solid tumours (RECIST) criteria, of patients with locally advanced / metastatic colorectal cancer treated with combination of irinotecan, oxalipla…

United Kingdom Apr 2009 – May 2013 Interventional
Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery
Finished Phase 3 1.535 patients NCT00660894

RATIONALE: Drugs used in chemotherapy, such as tegafur-uracil, leucovorin, and S-1, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving…

Japan Apr 2008 – Jul 2015 Interventional
Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma
Finished Phase 3 219 patients NCT00207831

RATIONALE: Drugs used in chemotherapy, such as 5-fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing and also as a radiosensibilisant. Radiation therapy uses…

France Jul 2004 – Feb 2008 Interventional
Combined with: Uracil
Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer
Finished Phase 2 NCT00004860

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of fluorour…

United States, Puerto Rico Oct 2000 Interventional
Combination Chemotherapy in Treating Patients With Resected Colon Cancer
Finished Phase 3 1.608 patients NCT00378716

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug is a way to kill more tumor cells. PURPOSE: Randomized phase III trial to determine the e…

Feb 1997 – Apr 2009 Interventional
Combined with: 5-FluorouracilUracil
Combination Chemotherapy and Radiation Therapy in Treating Patients With Colorectal Cancer
Finished Phase 1 30 patients NCT00002801

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Pha…

United States Apr 1996 – Dec 2009 Interventional