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NCT00384176

Terapia de primera línea para el cáncer colorrectal metastásico en combinación con FOLFOX.

Archived Fase 2

Descripción

El objetivo de este estudio es determinar si cediranib, en combinación con FOLFOX, es eficaz en el tratamiento del cáncer colorrectal metastásico, y comparar su eficacia con la de Avastin (bevacizumab) en combinación con FOLFOX.

Evidencia de la diana molecular en cáncer colorrectal

Aún no hay evidencia documentada en nuestra base para la diana o el fármaco de este ensayo. Esta sección crece a medida que se procesan nuevas publicaciones.

Criterios de Elegibilidad

Criterios de inclusión:

  • Diagnóstico clínico de cáncer de colon o recto.
  • No haber recibido tratamiento sistémico previo para enfermedad metastásica. Cualquier terapia adyuvante/neoadyuvante con oxaliplatino debe haberse administrado hace más de 12 meses antes de la inclusión en el estudio, y cualquier terapia adyuvante/neoadyuvante con 5-FU debe haberse administrado hace más de 6 meses antes de la inclusión en el estudio.

Criterios de exclusión:

  • Tratamiento previo con un inhibidor de VEGF, incluyendo bevacizumab y cediranib.
  • Hipertensión mal controlada.

Información del Ensayo

NCT00384176
Archived
Fase 2
1814 participantes
Ago 2006
Nov 2009

Ubicaciones280

Australia (40)
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Ashford
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Bedford Park
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Bendigo
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Box Hill
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Camperdown
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Coffs Harbour
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Darlinghurst
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East Melbourne
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Epping
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Herston
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Hobart
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Hornsby
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Kogarah
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Lismore
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Malvern
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Nedlands
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Port Macquarie
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Randwick
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South Brisbane
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St Leonards
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Tamworth
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Waratah
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Wodonga
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Woodville South
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Armidale, New South Wales
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Coffs Harbour, New South Wales
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Darlinghurst, New South Wales
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Hornsby, New South Wales
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Kogarah, New South Wales
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Port Macquarie, New South Wales
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Randwick, New South Wales
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St Leonards, New South Wales
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Tamworth, New South Wales
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Waratah, New South Wales
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South Brisbane, Queensland
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Ashford, South Australia
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Bedford Park, South Australia
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Woodville South, South Australia
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Hobart, Tasmania
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Epping, Victoria
Austria (7)
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Innsbruck
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Kundratstrasse 3
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Salzburg
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Vienna
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Wels
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Zams
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Kundratstrasse 3, Vienna
Belgium (15)
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Bonheiden
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Bruges
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Brussels (Woluwé-St-Lambert)
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Edegem
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Ghent
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Kortrijk
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Leuven
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Roeselare
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Bonheiden, Belgium
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Brussels (woluwe-st-lambert), Belgium
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Edegem, Belgium
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Ghent, Belgium
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Kortrijk, Belgium
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Leuven, Belgium
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Roeselare, Belgium
Canada (16)
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Montreal
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Calgary, Alberta
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Edmonton, Alberta
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Surrey, British Columbia
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Vancouver, British Columbia
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Sydney, Nova Scotia
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Barrie, Ontario
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Greater Sudbury, Ontario
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Newmarket, Ontario
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Scarborough Village, Ontario
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St. Catharines, Ontario
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Toronto, Ontario
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York, Ontario
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Lévis, Quebec
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Montreal, Quebec
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Québec, Quebec
Czechia (6)
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Brno
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Chomutov
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Kutná Hora
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Nová Ves pod Pleší
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Pardubice
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Tábor
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Alexandria
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Cairo
Finland (4)
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Helsinki
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Vaasa
France (6)
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Boulogne
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La Roche S YON
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Marseille
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Germany (9)
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Dresden
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Essen
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Hanover
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Heidelberg
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Tübingen
Hungary (5)
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Budapest
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Debrecen
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Pécs
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Szeged
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Tatabánya
India (14)
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Bangalore
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Chennai
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Hyderabad
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Jaipur
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Kolkata
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Mumbai
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Pune
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Sheikhpura
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Bhopal, Madhya Pradesh
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Pune, Maharashtra
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Jaipur, Rajasthan
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Varanasi, Uttar Prad
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Kolkata, West Bengal
Israel (7)
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Holon
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Kfar Saba
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Petah Tikva
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Tel Aviv
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Tel Litwinsky
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Tiberias
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Tzrifin
Italy (8)
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Ancona
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Napoli
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Roma
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Rozzano
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Genova, GE
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Rozzano, MI
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Roma, Roma
Latvia (1)
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Riga
Malta (2)
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Floriana
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Valletta
Philippines (4)
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Cebu City
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Davao City
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Molo
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Quezon City
Poland (8)
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Bytom
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Elblag
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Gdynia
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Krakow
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Lublin
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Poznan
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Rybnik
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Warsaw
Russia (5)
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Barnaul
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Novosibirsk
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Omsk
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Tomsk
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Tyumen
Slovakia (4)
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Bratislava
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Košice
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Nitra
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Prešov
South Africa (5)
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Cape Town
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Polokwane
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Port Elizabeth
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Pretoria
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Lyttelton Manor, South Africa
Spain (19)
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A Coruña
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Córdoba
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Granollers
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Hospitalet de Llobregat(Barcel
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Madrid
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Manresa
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Oviedo
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Valencia
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Zaragoza
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Córdoba, Andalusia
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Zaragoza, Aragon
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Barcelona, Catalonia
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Granollers, Catalonia
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Hospitalet de Llobregat(barcel, Catalonia
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Terrassa(barcelona), Catalonia
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A Coruña, Galicia
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Madrid, Madrid
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Oviedo, Principality of Asturias
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Valencia, Valencia
Taiwan (3)
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Tainan
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Taipei
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Taoyuan District, Taiwan
Thailand (6)
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Chiang Mai
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Rachathewi
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Songkhla
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Nakhonratchasima, Naimuang
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Chiang Mai, Thailand
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Songkhla, Thailand
Turkey (Türkiye) (3)
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Ankara
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Izmir
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Istanbul, Goztepe
Ukraine (17)
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Cherkassy
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Chernihiv
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Chernivtsi
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Dnipropetrovsk
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Donetsk
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Ivano-Frankivsk
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Kharkiv
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Kherson
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Kiev
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Kyiv
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Luhansk
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Lviv
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Poltava
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Simferopol
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Sumy
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Ternopil
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Uzhhorod
United Kingdom (16)
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Bebington
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Bournemouth
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Bradford
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Guildford
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Ipswich
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London
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Maidstone
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Newcastle upon Tyne
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Northwood
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Poole
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Stockport
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Sutton
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Southampton, Hampshire
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Maidstone, Kent
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Northwood, Middlesex
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Sutton, Surrey
United States (44)
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Anniston, Alabama
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Birmingham, Alabama
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Casa Grande, Arizona
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Tucson, Arizona
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Hot Springs, Arkansas
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Palm Springs, California
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San Diego, California
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Fairfield, Connecticut
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Stamford, Connecticut
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Bay Pines, Florida
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Fort Meyers, Florida
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Port Saint Lucie, Florida
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Galesburg, Illinois
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Park Ridge, Illinois
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Quincy, Illinois
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Layfayette, Indiana
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New Albany, Indiana
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Alexandria, Louisiana
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Layfayette, Louisiana
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Hagerstown, Maryland
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Ann Arbor, Michigan
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Ypsilanti, Michigan
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St Louis, Missouri
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Great Falls, Montana
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Lincoln, Nebraska
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Summit, New Jersey
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Fresh Meadows, New York
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Northport, New York
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Rochester, New York
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Fayetteville, North Carolina
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New Bern, North Carolina
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Bismarck, North Dakota
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Cincinnati, Ohio
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Middletown, Ohio
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Zanesville, Ohio
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Coos Bay, Oregon
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Hilton Head Island, South Carolina
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Chattanooga, Tennessee
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Knoxville, Tennessee
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Nashville, Tennessee
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Austin, Texas
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White River Junction, Vermont
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Abingdon, Virginia
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Alexandria, Virginia
Vietnam (4)
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Hanoi
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Ho Chi Minh City
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Hanoi, Vietnam
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Ho Chi Minh City, Vietnam

Fuente Oficial

Ver en ClinicalTrials.gov