VVD-133214 (Not yet branded)

Other Medications

US Experimental IV 1 Clinical Trials
Unknown molecular target

Description

VVD-133214 is an experimental compound currently in early-phase clinical development for treatment of advanced solid tumors, including colorectal cancer. Based on available trial data, this agent is being evaluated specifically in patients with microsatellite instability-high (MSI-H) tumors as both a single agent and in combination therapy. The drug appears to be designed for tumor-agnostic treatment approaches, targeting cancers with specific biomarker characteristics rather than organ-specific indications.

Mechanism of Action

The precise molecular mechanism of action for VVD-133214 has not been publicly disclosed in available clinical trial documentation. Given its evaluation in MSI-H tumors and tumor-agnostic approach, it likely targets pathways related to DNA damage response, immune evasion, or mismatch repair deficiency that characterizes these specific tumor types.

Molecular Targets

Side Effects

Side effect profile not yet established in published literature Fatigue Nausea Decreased appetite Diarrhea Skin reactions Laboratory abnormalities Infusion-related reactions

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06004245 Phase 1
Recruiting
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
United States, Australia, Belgium, Canada, Denmark, France, Malaysia, South Kore