Description
TL938 is an experimental medication currently being studied in clinical trials for specific types of colorectal cancer. It is being investigated as a potential treatment for metastatic or recurrent HER2-positive colorectal cancer that cannot be surgically removed. This means the cancer has spread and the cancer cells have too much of the HER2 protein on their surface. The trial combines TL938 with trastuzumab, another medication that targets HER2. The goal of the ongoing Phase 2 trial is to find the best dose of TL938 and see how well it works when given with trastuzumab in this patient group. TL938 is not yet approved for use in colorectal cancer or any other condition.
Mechanism of Action
TL938 is being studied in combination with trastuzumab for HER2-positive colorectal cancer. Trastuzumab targets the HER2 protein found on the surface of some cancer cells. The specific way TL938 works (its mechanism of action) is still being investigated in clinical trials. It is being evaluated for its potential to enhance the effect of trastuzumab or target other pathways involved in HER2-positive cancer growth.
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.