TL938

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

TL938 is an experimental medication currently being studied in clinical trials for specific types of colorectal cancer. It is being investigated as a potential treatment for metastatic or recurrent HER2-positive colorectal cancer that cannot be surgically removed. This means the cancer has spread and the cancer cells have too much of the HER2 protein on their surface. The trial combines TL938 with trastuzumab, another medication that targets HER2. The goal of the ongoing Phase 2 trial is to find the best dose of TL938 and see how well it works when given with trastuzumab in this patient group. TL938 is not yet approved for use in colorectal cancer or any other condition.

Mechanism of Action

TL938 is being studied in combination with trastuzumab for HER2-positive colorectal cancer. Trastuzumab targets the HER2 protein found on the surface of some cancer cells. The specific way TL938 works (its mechanism of action) is still being investigated in clinical trials. It is being evaluated for its potential to enhance the effect of trastuzumab or target other pathways involved in HER2-positive cancer growth.

Side Effects

As TL938 is an investigational drug in early-phase clinical trials The full range of potential side effects is still being evaluated. Information about side effects from the ongoing Phase 2 trial (NCT06589830) is not yet available in detail. Participants in the trial will be closely monitored for any adverse events. Common side effects associated with trastuzumab Which is being used in combination Can include heart problems Infusion reactions And fatigue. Specific side effects related to TL938 itself are still being determined.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06589830 Phase 2
Recruiting
TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer
China