TAS-116

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

TAS-116 is an investigational medication currently being studied in clinical trials. It is being evaluated as a potential treatment for various types of cancer, including colorectal cancer. The trials are in early phases (Phase 1), meaning they primarily focus on determining the safest dose and understanding how the drug is processed by the body. TAS-116 is being tested alone and in combination with other cancer treatments, such as chemotherapy agents (like 5-Fluorouracil, Gemcitabine, Nab-Paclitaxel) and targeted therapies (like Bevacizumab, Ramucirumab). Some trials are specifically looking at patients whose tumors have certain genetic changes (mutations) like EGFR, KRAS, MET, NRAS, VEGF, or specific levels of PD-L1 expression. The goal of these early trials is to assess the safety and potential effectiveness of TAS-116 in these patient groups. It is not yet approved for use in colorectal cancer.

Mechanism of Action

TAS-116 is being investigated as a potential cancer treatment. The specific way it works (its mechanism of action) is still being studied in clinical trials. It is designed to target processes involved in cancer cell growth and survival. Further research is needed to fully understand its molecular target and how it interacts with cancer cells.

Side Effects

As TAS-116 is an investigational drug in early-phase clinical trials The full range of potential side effects is still being evaluated. The primary focus of Phase 1 trials is to assess safety and determine the maximum tolerated dose. Common side effects observed in early cancer drug trials can vary widely depending on the drug and the patients involved. Specific side effect data for TAS-116 is not yet available publicly from these early trials. Researchers will continue to monitor patients closely to identify and characterize any side effects.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT04999761 Phase 1
Recruiting
AB122 Platform Study
Japan