Streptozocin (Zanosar (brand name), Streptozocin (generic))

Other Medications

ES Hospital use 1 Clinical Trials

Description

Streptozocin is an alkylating antineoplastic antibiotic derived from Streptomyces achromogenes. While it is a real chemotherapy agent, it is not typically used for colorectal cancer treatment.

Mechanism of Action

It works by cross-linking DNA strands and interfering with DNA replication and transcription in rapidly dividing cells.

Side Effects

Severe nausea and vomiting Nephrotoxicity (kidney damage) Hepatotoxicity (liver toxicity) Hypoglycemia

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT00003543 Phase 1
Archived
Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
United States