Selenium (Available as generic selenium supplements, Selenomethionine, Sodium selenite)
Other Medications
Description
Selenium is an essential trace mineral that functions as a micronutrient supplement used in colorectal cancer prevention research. It is classified as a dietary supplement and antioxidant compound that has been studied for its potential role in preventing the development of adenomatous colorectal polyps, which are precancerous lesions that can progress to colorectal cancer. Selenium supplementation has been evaluated in large-scale prevention trials focusing on reducing polyp recurrence in patients with a history of colorectal adenomas.
Mechanism of Action
Selenium acts as a cofactor for selenoproteins, including glutathione peroxidases and thioredoxin reductases, which provide antioxidant protection against oxidative stress and DNA damage. These selenoenzymes help maintain cellular redox balance and may reduce inflammation in the colonic epithelium. The antioxidant properties of selenium may help prevent the oxidative damage that contributes to the initiation and progression of colorectal carcinogenesis.
Molecular Targets
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
Quick Info
| Brand Name | Available as generic selenium supplements, Selenomethionine, Sodium selenite |
| Category | Other Medications |
 Status | FDA Approved |
| Administration | Oral |
| Clinical Trials | 2 |
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.