Ropidoxuridine (Not yet branded)
Other Medications
Description
Ropidoxuridine (IPdR) is a halogenated pyrimidine nucleoside analog that functions as a radiosensitizing agent in cancer treatment. This compound is specifically designed to enhance the effectiveness of radiation therapy by incorporating into DNA and making cancer cells more vulnerable to radiation damage. In colorectal cancer treatment, ropidoxuridine is being evaluated in combination with standard chemotherapy agents like capecitabine during radiation therapy protocols, particularly for rectal cancer patients.
Mechanism of Action
Ropidoxuridine works by incorporating into the DNA of rapidly dividing cancer cells during DNA synthesis, replacing thymidine in the DNA structure. Once incorporated, the halogenated nucleo
Molecular Targets
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
Quick Info
| Brand Name | Not yet branded |
| Category | Other Medications |
 Status | Experimental |
 EMA Status | Not submitted to EMA |
 Spain Access | Not available |
| Administration | IV |
| Clinical Trials | 2 |
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.