Rimegepant (** Nurtec ODT (orally disintegrating tablet) **)

Other Medications

ES Not funded other indication 1 Clinical Trials

Description

Rimegepant is not indicated for the treatment of colorectal cancer. It is used as an acute treatment for migraine and cluster headache in adults, with efficacy demonstrated in clinical trials showing rapid onset of action and sustained relief without sedation or cardiovascular effects.

Mechanism of Action

Rimegepant is a small molecule antagonist of the calcitonin gene-related peptide (CGRP) receptor, which plays a role in migraine pathophysiology by mediating neurogenic inflammation and pain.

Side Effects

Nausea; xerostomia; oropharyngeal pain

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06999252 Phase 2
Not yet recruiting
Rimegepant Combined With PD-1 in Liver Metastasis Colorectal Cancer Patients
China