Propranolol (** Inderal, Inderal LA, InnoPran XL, Hemangeol (Generic: Propranolol) **)
Other Medications
Description
Propranolol is not primarily used in the treatment of colorectal cancer. It has been investigated for its potential role as an anti-angiogenic agent but lacks specific clinical evidence in this context. Its use remains experimental and off-label in oncology.
Mechanism of Action
Propranolol is a non-selective beta-adrenergic receptor antagonist that also has intrinsic sympathomimetic activity and membrane-stabilizing effects.
Side Effects
Hypotension; bradycardia; fatigue; dizziness; depression; insomnia; nausea; diarrhea; constipation
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
NCT03919461
Phase 2
Recruiting
Colorectal Metastasis Prevention International Trial 2
Israel
NCT07549906
Phase 2
Not yet recruiting
Neoadjuvant Iparomlimab/Tuvonralimab Plus CAPEOX Versus Iparomlimab/Tuvonralimab Plus CAPEOX and Propranolol for Locally Advanced pMMR Colon Cancer: A Prospective, Single-Center, Multi-Cohort Study