Propofol (Diprivan, Propoven, Fresofol)
Other Medications · Approved since 1989
Description
Propofol is a short-acting intravenous general anesthetic agent used for the induction and maintenance of anesthesia during surgical procedures for colorectal cancer patients. This lipophilic phenolic compound provides rapid onset of anesthesia and allows for quick recovery due to its favorable pharmacokinetic profile. In colorectal cancer treatment, propofol is administered during surgical resection procedures, with recent clinical research examining whether the choice of anesthetic agent may influence cancer recurrence and postoperative outcomes.
Mechanism of Action
Propofol enhances the activity of gamma-aminobutyric acid (GABA) at GABA-A receptors in the central nervous system, leading to increased chloride ion influx and neuronal hyperpolarization. This results in dose-dependent sedation progressing to general anesthesia through depression of neuronal activity in the brain and spinal cord.
Molecular Targets
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
Quick Info
| Brand Name | Diprivan, Propoven, Fresofol |
| Category | Other Medications |
 Status | FDA Approved |
 EMA Status | EMA Approved |
 Spain Access | Hospital use other indication |
| Administration | IV |
| Year Approved | 1989 |
| Clinical Trials | 5 |
Related Medications
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.