OMP-131R10

Other Medications

Description

OMP-131R10 is an experimental medication currently being studied in clinical trials for certain types of cancer, including colorectal cancer. It is being investigated as a potential treatment option for patients whose colorectal cancer has spread (metastatic) and has progressed after at least one previous treatment. In trials for colorectal cancer, OMP-131R10 is being tested in combination with a standard chemotherapy regimen called FOLFIRI (which includes the drugs 5-Fluorouracil, Irinotecan, and Leucovorin). The goal of these early-phase trials is primarily to assess the safety and determine the appropriate dosage of OMP-131R10 when given with FOLFIRI. It is important to note that OMP-131R10 is not yet approved for use in colorectal cancer and is only available within the context of clinical trials.

Mechanism of Action

OMP-131R10 is designed to target specific proteins involved in the growth and spread of cancer cells. The specific proteins targeted by OMP-131R10 are being characterized in clinical trials. It is administered intravenously (IV).

Side Effects

As OMP-131R10 is an investigational drug Its full range of side effects is still being evaluated in ongoing clinical trials. The most informative trial (NCT02482441) is a Phase 1 study focused on safety and dosage. Therefore Specific common side effects cannot be definitively listed based on the provided data. Patients participating in trials are closely monitored for any adverse events.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT02482441 Phase 1
Archived
A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10
United States