NGM120

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

NGM120 is an investigational medication currently being studied in clinical trials for various advanced solid tumors, including pancreatic cancer and prostate cancer. It is not yet approved for treating colorectal cancer (CRC). In CRC trials, NGM120 has been studied in combination with other drugs like gemcitabine and nab-paclitaxel (Abraxane). The goal of these early-phase trials is primarily to assess the safety and tolerability of NGM120, determine the right dosage, and see if it has any anti-cancer activity in patients with advanced solid tumors. It is important to note that NGM120 is still in early stages of development and its effectiveness and safety profile in CRC are still under investigation.

Mechanism of Action

NGM120 is being investigated as a potential treatment for certain cancers. The specific way it works (its mechanism of action) is still being studied in clinical trials. It is designed to target specific pathways involved in tumor growth and survival. Researchers are evaluating how NGM120 interacts with cancer cells and its potential impact on tumor progression.

Side Effects

As NGM120 is an investigational drug in early-phase clinical trials The full range of potential side effects is still being evaluated. The most informative trial (NCT04068896) studied NGM120 in patients with advanced solid tumors. Common side effects observed in early trials often include fatigue Nausea Decreased appetite And other general symptoms related to cancer or its treatment. Specific side effects related to NGM120 itself are still being determined through ongoing research. Patients participating in trials are closely monitored for any adverse events.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT04068896 Phase 1
Archived
Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
United States