KZR-261 (Not yet branded)

Other Medications

US Experimental EU Experimental ES Not available Oral 1 Clinical Trials
Undisclosed kinase target

Description

KZR-261 is an oral small molecule inhibitor designed to target solid tumors including colorectal cancer. This compound is being developed as a targeted therapy for patients with advanced solid malignancies who have limited treatment options. Based on its development profile, KZR-261 appears to be part of a tumor-agnostic approach, meaning it targets specific molecular pathways present across different cancer types rather than being specific to colorectal cancer alone.

Mechanism of Action

KZR-261 likely functions by inhibiting specific protein kinases or signaling pathways that are critical for tumor cell survival and proliferation. The exact molecular target and mechanism of action have not been fully disclosed in publicly available information, but it appears to interfere with cellular processes that drive cancer growth and metastasis.

Molecular Targets

Side Effects

Fatigue Nausea Diarrhea Decreased appetite Rash Elevated liver enzymes Neutropenia Thrombocytopenia

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT05047536 Phase 1
Archived
KZR-261 in Subjects With Advanced Solid Malignancies
United States