Description
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that serves as supportive care in colorectal cancer treatment for managing pain, inflammation, and fever. It is commonly used to alleviate treatment-related discomfort and improve quality of life during cancer therapy.
Mechanism of Action
Ibuprofen works by inhibiting cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2, which reduces the production of prostaglandins responsible for pain, inflammation, and fever. This inhibition helps control inflammatory responses and provides analgesic effects in cancer patients.
Side Effects
Gastrointestinal upset
Nausea
Heartburn
Dizziness
Headache
Drowsiness
Stomach ulcers
Increased bleeding risk
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
NCT04432597
Phase 1
Active, not recruiting
HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers
United States