Description
GM103 is an experimental medication currently being studied in clinical trials for various solid tumors, including colorectal cancer. It is being investigated as a potential treatment for locally advanced, unresectable, refractory, and/or metastatic disease. The trials are in Phase 1, which means they are primarily focused on determining the safest dose (Maximum Tolerated Dose or MTD) and understanding how patients tolerate the drug, both when given alone (monotherapy) and in combination with another immunotherapy drug called pembrolizumab. The goal is to see if GM103 is safe and if it shows any early signs of effectiveness in shrinking tumors or slowing their growth. It is administered as an injection directly into the tumor (intratumoral injection). It is important to remember that GM103 is not yet approved for treating colorectal cancer or any other condition.
Mechanism of Action
GM103 is being studied as a potential cancer therapy. The specific way it works (its mechanism of action) is still under investigation in clinical trials. It is administered directly into the tumor tissue. Trials are evaluating its effects both as a single agent and in combination with pembrolizumab, an immunotherapy drug.
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.