Gb1275

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

Gb1275 is an investigational medication currently being studied in clinical trials for various advanced solid tumors, including colorectal cancer. It is being evaluated to see if it can help slow or stop the growth of cancer cells. In the context of colorectal cancer, it has been studied in combination with other treatments like gemcitabine, nab-paclitaxel, and pembrolizumab. Gb1275 is not yet approved for use in colorectal cancer or any other cancer type. The trials are in early phases (Phase 1), meaning they are primarily focused on determining the safety and appropriate dosage of the drug, as well as looking for early signs of effectiveness.

Mechanism of Action

The specific way Gb1275 works (its mechanism of action) is still being investigated in clinical trials. It is designed to target processes involved in cancer cell growth and survival. Researchers are studying how it interacts with cancer cells and the body's immune system to understand its potential benefits.

Side Effects

As Gb1275 is an investigational drug in early-phase trials The full range of potential side effects is still being evaluated. Information from the Phase 1 trial (NCT04060342) would provide more specific details But generally Side effects in early trials can include fatigue Nausea Changes in blood counts And other effects related to how the body processes the drug. More detailed information about side effects will become available as clinical trials progress.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT04060342 Phase 1
Archived
GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma
United States, United Kingdom