Falimarev

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

Falimarev is an investigational vaccine therapy being studied for colorectal cancer patients who have had surgery to remove liver or lung metastases (cancer that has spread). It is currently in Phase 2 clinical trials. The goal of this vaccine is to help the patient's own immune system recognize and attack any remaining cancer cells. It is given in combination with other treatments, such as Inalimarev and Sargramostim, in some studies. It is not yet approved for use in colorectal cancer.

Mechanism of Action

Falimarev is a type of cancer vaccine. It works by using components from the cancer cells (like CEA and MUC-1) along with immune-stimulating molecules (TRICOM) delivered via viral vectors (vaccinia and fowlpox). This combination is designed to activate the patient's immune system, specifically dendritic cells, to recognize and target cancer cells expressing CEA and MUC-1. The vaccine aims to create a long-term immune response against the cancer.

Side Effects

As Falimarev is an investigational vaccine Specific side effect data is still being collected in clinical trials. Common side effects associated with vaccines and immune therapies can include flu-like symptoms (fever Chills Fatigue) Injection site reactions (pain Redness Swelling) And potentially more serious immune-related adverse events. The specific side effects and their frequency are still being evaluated in ongoing trials.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT00103142 Phase 2
Archived
Vaccine Therapy in Treating Patients With Liver or Lung Metastases From Colorectal Cancer
United States

Quick Info

CategoryOther Medications
EU EMA StatusExperimental
ES Spain AccessNot available
Clinical Trials1
View Clinical Trials Back to Drug Glossary

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Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.