ETC-1922159

Other Medications

Description

ETC-1922159 is an experimental drug currently being studied in clinical trials for advanced solid tumors, including colorectal cancer. It is being investigated to determine its safety, how it is processed by the body (pharmacokinetics), and its effects on the body (pharmacodynamics). Trials have evaluated ETC-1922159 alone and in combination with pembrolizumab, an immunotherapy drug. The trials included patients with advanced or metastatic solid tumors for whom standard treatments were not available or had failed. The studies are designed to find the safest dose and understand how the drug works. The trials specifically included patients with microsatellite stable (MSS) tumors. This drug is still in early-phase development (Phase 1).

Mechanism of Action

ETC-1922159 is being studied as a potential treatment for advanced solid tumors. The specific way it works (its mechanism of action) is being investigated in clinical trials. It is being tested both as a single agent and in combination with pembrolizumab.

Side Effects

As ETC-1922159 is an investigational drug in Phase 1 trials Its side effects are still being carefully evaluated. The primary goal of Phase 1 trials is to assess safety and determine the maximum tolerated dose. Specific side effects have not been fully characterized or reported publicly for this drug in the context of colorectal cancer. Patients participating in these trials are closely monitored for any adverse events.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT02521844 Phase 1
Active, not recruiting
A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours
United States, Singapore