E7046

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

E7046 is an experimental drug being studied by Adlai Nortye Biopharma Co., Ltd. It is currently in Phase 1 clinical trials for colorectal cancer, specifically locally advanced rectum cancer. This phase of testing focuses on determining the safety and appropriate dosage of E7046 when given in combination with standard preoperative chemoradiotherapy (treatment using radiation and chemotherapy before surgery). The goal is to see if this combination can improve the chances of clear surgical margins (meaning the cancer is completely removed) in patients where surgery alone might not be sufficient. The study also includes an expansion part to evaluate the effectiveness of the combination at the recommended dose.

Mechanism of Action

E7046 is being investigated as a potential treatment for locally advanced rectum cancer. The specific way it works (its mechanism of action) is still being studied in clinical trials. It is being tested in combination with chemoradiotherapy to see if it can improve outcomes before surgery.

Side Effects

As E7046 is an investigational drug in early-phase trials (Phase 1) The full range of potential side effects is still being evaluated. The primary focus of Phase 1 trials is to assess safety and determine the highest dose that can be given without unacceptable side effects. Specific side effect data from this trial (NCT03152370) is not available in this summary But participants in clinical trials are closely monitored for any adverse events.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT03152370 Phase 1
Archived
Preoperative Radiotherapy and E7046 in Rectum Cancer
United States, Poland, United Kingdom

Quick Info

CategoryOther Medications
EU EMA StatusExperimental
ES Spain AccessNot available
Clinical Trials1
View Clinical Trials Back to Drug Glossary

Related Medications

Uracil
Other Medications
786 trials
Leucovorin
Other Medications
647 trials
Paclitaxel
Other Medications
54 trials
Trifluridine
Other Medications
50 trials
Cyclophosphamid
Other Medications
50 trials
Cyclophosphamide
Other Medications
49 trials

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.