Crlx101

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

CRLX101 is under investigation for the treatment of colorectal cancer. It has shown promise in preclinical studies but its efficacy and safety profile are still being evaluated in clinical trials; it has not yet been approved by regulatory agencies like the FDA.

Mechanism of Action

CRLX101 is an investigational nanoparticle drug that encapsulates the topoisomerase I inhibitor irinotecan, designed to improve its pharmacokinetics and reduce toxicity.

Side Effects

Neutropenia; diarrea; fatiga; náuseas; vómito

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT02010567 Phase 1
Archived
Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer
United States