BNT314

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

BNT314 is an investigational medication being studied by BioNTech SE for advanced colorectal cancer. It is currently in Phase 1 clinical trials. These early trials are primarily focused on determining the safety of BNT314, often in combination with other investigational drugs (like BNT327) and standard chemotherapy. The goal is to find the right dose and understand how patients tolerate the treatment. Later phases of the trial (like Part C of NCT07079631) will compare BNT314 plus BNT327 plus chemotherapy to standard chemotherapy alone to see if the combination can shrink tumors or slow their growth better. The trials are actively recruiting participants. BNT314 is being studied in patients with MSI-H or MSS tumors.

Mechanism of Action

BNT314 is an investigational treatment. The specific way it works (its mechanism of action) is currently being studied in clinical trials. It is being investigated in combination with other agents to treat advanced colorectal cancer.

Side Effects

As BNT314 is an investigational drug in early-phase clinical trials (Phase 1) The full range of potential side effects is still being evaluated. The primary focus of these early trials is to assess safety and determine the maximum tolerated dose. Information about specific side effects will become clearer as the trials progress.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT07079631 Phase 1
Recruiting
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
United States, Germany, Japan, Spain, United Kingdom