BMS-986504

Other Medications

Description

BMS-986504 is an investigational medication currently being studied by Bristol-Myers Squibb. It is being evaluated in clinical trials for patients with advanced or metastatic solid tumors, including colorectal cancer, specifically in those whose tumors have a specific genetic feature called homozygous MTAP deletion. Clinical trials are exploring BMS-986504 both as a single treatment (monotherapy) and in combination with other cancer drugs. The goal of these trials is to determine the safety and effectiveness of BMS-986504 in these patients. It is important to note that BMS-986504 is not yet approved for use in colorectal cancer or any other condition.

Mechanism of Action

BMS-986504 is being investigated as a potential treatment for cancers with MTAP deletion. MTAP deletion is a specific genetic change found in some tumors. The drug's specific mechanism of action (how it works at a molecular level) is still being studied in clinical trials. Researchers are evaluating how it affects cancer cells, particularly in the context of MTAP deletion.

Side Effects

As BMS-986504 is an investigational drug in early-phase clinical trials (Phase 1 and Phase 2) The full range of potential side effects is still being determined. Information about side effects is being carefully collected and analyzed during these trials to understand the drug's safety profile. Specific side effect data for colorectal cancer patients is not yet available publicly But common side effects observed in early trials for solid tumors are being monitored.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06672523 Phase 1
Recruiting
A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion
Hungary, Spain
NCT07492680 Phase 2
Not yet recruiting
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
United States, Belgium, Canada, China, France, Germany, Hong Kong, Ireland, Ital