Bdc-1001

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

BDC-1001 is an experimental drug currently under investigation for the treatment of colorectal cancer, particularly in patients with mutations or alterations in the Wnt/ -catenin pathway; its clinical efficacy and safety are still being evaluated in early-phase clinical trials.

Mechanism of Action

BDC-1001 is an investigational agent that targets the Wnt/ -catenin signaling pathway, which is often aberrantly activated in colorectal cancer; it inhibits ?-catenin-mediated transcription by binding to T-cell factor (TCF) proteins.

Side Effects

Hypertension; fatigue; nausea; vomiting

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT04278144 Phase 1
Terminated
A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors
United States, France, South Korea, Spain