AWT020

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

AWT020 is an investigational medication currently being studied in clinical trials for various advanced cancers, including colorectal cancer. It is being evaluated in Phase 1 trials to determine its safety and how well it is tolerated, both when given alone (monotherapy) and in combination with other standard cancer treatments like chemotherapy (e.g., capecitabine, oxaliplatin, paclitaxel, pemetrexed) or targeted therapies (e.g., bevacizumab, renvastinib). These early-stage trials are designed to find the best dose and understand potential side effects before testing it in larger groups of patients. The trials are looking at patients with specific characteristics, such as those with ALK mutations, EGFR mutations, MSI-H status, or certain levels of PD-L1 expression, which might suggest the drug could be effective for them. AWT020 is not yet approved for treating colorectal cancer or any other cancer.

Mechanism of Action

AWT020 is being studied as a potential treatment for advanced cancers. The specific way it works (its mechanism of action) is currently being investigated in clinical trials. It is designed to target cancer cells, and researchers are exploring its potential effects on tumor growth and spread. The trials are also looking at how it interacts with the immune system and other cancer therapies.

Side Effects

As AWT020 is an investigational drug in early-phase clinical trials (Phase 1) The full range and frequency of potential side effects are still being evaluated. The primary goal of these initial trials is to assess the safety and tolerability of the drug. Information about specific side effects will become clearer as the trials progress. Patients participating in these trials are closely monitored for any adverse events.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06839105 Phase 1
Recruiting
A Clinical Study to Evaluate the Safety and Tolerability of AWT020 in Patients With Advanced Malignancies
China