Anastrozole (** - Arimidex (brand name) - Generic anastrozole (various manufacturers) **)
Other Medications
Description
Anastrozole is primarily used in the treatment of breast cancer and not typically indicated for colorectal cancer. It has shown efficacy in postmenopausal women with hormone receptor-positive breast cancer as an adjuvant therapy or for advanced disease, but there are no established clinical uses in CCR.
Mechanism of Action
Anastrozole is a nonsteroidal aromatase inhibitor that irreversibly binds to the aromatase enzyme, blocking the conversion of androgens to estrogens.
Side Effects
Hot flashes; arthralgia; increased risk of fractures; bone pain; joint stiffness
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
NCT05768139
Phase 1
Recruiting
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
United States, Belgium, France, Germany, Ireland, Italy, Japan, Netherlands, Spa
NCT05307705
Phase 1
Active, not recruiting
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
United States, Australia, Belgium, Canada, China, France, Germany, Japan, Singap