Alt-803 (Not yet branded)
Other Medications
Description
Alt-803 is a super-agonist interleukin-15 (IL-15) complex that functions as an immunotherapy agent. In colorectal cancer treatment, it is being used in combination with cancer vaccines, particularly those targeting carcinoembryonic antigen (CEA)-expressing tumors. The medication works to enhance immune system activation and tumor recognition in patients with CEA-positive colorectal cancers.
Mechanism of Action
Alt-803 binds to and activates the IL-15 receptor complex on immune cells, particularly natural killer (NK) cells and CD8+ T cells. This activation leads to enhanced proliferation, survival, and cytotoxic function of these immune effector cells against cancer cells. The super-agonist properties provide more potent and sustained immune stimulation compared to native IL-15.
Molecular Targets
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.
Clinical Trials
Quick Info
| Brand Name | Not yet branded |
| Category | Other Medications |
 Status | Experimental |
 EMA Status | Experimental |
 Spain Access | Not available |
| Administration | Subcutaneous |
| Clinical Trials | 2 |
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.