ADG126

Other Medications

EU Experimental ES Not available 1 Clinical Trials

Description

ADG126 is an investigational medication currently being studied in clinical trials for colorectal cancer. It is being evaluated in combination with pembrolizumab (an immunotherapy drug) before surgery (neoadjuvant setting) for patients with locally advanced (Stage II or III) colorectal cancer. The goal of this trial is to see if this combination treatment can shrink tumors or improve outcomes before the main treatment (surgery). This treatment is not yet approved for use in colorectal cancer.

Mechanism of Action

ADG126 is being studied in combination with pembrolizumab. Pembrolizumab is an immunotherapy drug that helps the body's immune system fight cancer. The specific mechanism of action of ADG126 is being investigated in clinical trials. It is being given before surgery in combination with pembrolizumab to see if it can improve outcomes for patients with locally advanced colorectal cancer.

Side Effects

ADG126 is an investigational drug And its side effects are still being evaluated in ongoing clinical trials. Side effects observed in trials involving ADG126 and pembrolizumab may include those associated with both drugs. Common side effects of pembrolizumab can include fatigue Rash Diarrhea Itching Cough Nausea Decreased appetite Vomiting Abdominal pain And musculoskeletal pain. The specific side effect profile of ADG126 is still being determined.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06846268 Phase 2
Recruiting
Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer
Singapore