ADG106

Other Medications

Description

ADG106 is an investigational medication currently being studied in clinical trials. It is being investigated for its potential use in combination with chemotherapy for certain types of cancer. In colorectal cancer, one early-phase trial (Phase 1) is exploring ADG106 in combination with standard chemotherapy regimens. The trial is being conducted to determine the safety and tolerability of ADG106 when given with chemotherapy. The specific role of ADG106 in treating colorectal cancer is still under investigation.

Mechanism of Action

The specific mechanism of action for ADG106 is being investigated in clinical trials. It is being studied in combination with chemotherapy drugs like cyclophosphamide, doxorubicin, and paclitaxel. The goal is to see if adding ADG106 to standard chemotherapy improves outcomes or helps patients who may not respond well to chemotherapy alone. The drug targets specific pathways involved in cancer cell growth and survival, but the exact molecular target is still being characterized.

Side Effects

As ADG106 is an investigational drug in early-phase trials Its side effect profile is still being evaluated. The most informative trial (NCT0527577) studied ADG106 in combination with chemotherapy for breast cancer. Side effects observed in that trial would likely be relevant Potentially including those associated with the chemotherapy agents (like nausea Fatigue Hair loss Low blood counts) and potentially additional side effects specific to ADG106. The specific side effects related to ADG106 in colorectal cancer patients are still being determined in ongoing trials.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT05275777 Phase 1
Active, not recruiting
A Phase Ib Safety lead-in, Followed by Phase II Trial of ADG106 in Combination With Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer
Singapore