Description
Adct-301 is an investigational medicine being studied by ADC Therapeutics S.A. It is currently in Phase 1 clinical trials for certain advanced solid tumors, including colorectal cancer. This trial is designed to determine the safety and how well the drug is tolerated at different doses (Phase 1a) and to see if it has any activity against the cancer (Phase 1b). The trial combines Adct-301 with pembrolizumab, an immunotherapy drug. The study includes patients with different types of colorectal cancer, including those with MSI-H (microsatellite instability-high) and MSS (microsatellite stable) tumors, and those with varying levels of PD-L1 expression. Adct-301 is not yet approved for treating colorectal cancer.
Mechanism of Action
Adct-301 is being investigated as a potential treatment for certain cancers. The specific way it works (its mechanism of action) is being studied in clinical trials. It is designed to target cancer cells.
Side Effects
Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.