Abt-165

Other Medications

EU Experimental ES med_spain_not_available 1 Clinical Trials

Description

Abt-165 is an investigational drug being studied by AbbVie for the treatment of metastatic colorectal cancer. It is currently in Phase 2 clinical trials. The main trial (NCT03368859) is evaluating Abt-165 when given with FOLFIRI (a chemotherapy regimen containing irinotecan and leucovorin) compared to bevacizumab (a common targeted therapy) plus FOLFIRI. This trial is for patients whose cancer has spread and who have previously received treatment with fluoropyrimidine, oxaliplatin, and bevacizumab. The goal is to see if adding Abt-165 to FOLFIRI is more effective and can be tolerated compared to the standard FOLFIRI plus bevacizumab regimen. Abt-165 is not yet approved for use in colorectal cancer.

Mechanism of Action

The specific mechanism of action for Abt-165 is being investigated in clinical trials. It is being studied in combination with standard chemotherapy (FOLFIRI) and another targeted therapy (bevacizumab) for metastatic colorectal cancer. The trial aims to determine if Abt-165 can improve outcomes when added to this treatment combination.

Side Effects

As Abt-165 is an investigational drug in Phase 2 trials Comprehensive safety data is still being collected. The side effects observed in the NCT03368859 trial will help determine the drug's safety profile. Information about specific side effects is not yet widely available to the public But will be reported as the trials progress.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT03368859 med_phase_prefix2
Archived
A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab
United States, Belgium, Canada, South Korea, Spain, Taiwan

Quick Info

CategoryOther Medications
EU Estado EMAExperimental
ES Acceso Españamed_spain_not_available
Clinical Trials1
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Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.