AB928

Other Medications

EU Not submitted to EMA ES Not available 1 Clinical Trials

Description

AB928 is an investigational medication currently being studied by Hoffmann-La Roche. It is being evaluated in clinical trials for patients with metastatic colorectal cancer (mCRC) that has not responded to standard first- and second-line treatments. The goal of these early-phase trials (Phase 1) is primarily to assess the safety and tolerability of AB928, often in combination with other cancer therapies like immunotherapy agents (e.g., Atezolizumab, Selicrelumab) or targeted therapies (e.g., Bevacizumab, Regorafenib). Researchers are also looking for early signs that the treatment might be effective in shrinking tumors or slowing disease progression. AB928 is not yet approved for use in colorectal cancer or any other condition.

Mechanism of Action

The specific way AB928 works (its mechanism of action) is currently being investigated in clinical trials. It is being studied in combination with other drugs, which may influence its effects. The trials aim to understand how AB928 interacts with the body and affects cancer cells.

Side Effects

As AB928 is an investigational drug in early-phase clinical trials The full range of potential side effects is still being determined. Safety and tolerability are key focuses of these trials. Specific side effects observed in the NCT03555149 trial (Morpheus-CRC) would depend on the specific combination of drugs used in each treatment arm. Patients participating in these trials are closely monitored for any adverse events.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT03555149 Phase 1
Archived
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)
United States, Australia, France, South Korea, Switzerland

Quick Info

CategoryOther Medications
EU EMA StatusNot submitted to EMA
ES Spain AccessNot available
Clinical Trials1
View Clinical Trials Back to Drug Glossary

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Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.