A166

Other Medications

EU Experimental ES Not available 2 Clinical Trials

Description

A166 is an experimental medication currently being studied in clinical trials for certain types of cancer. Specifically, it is being investigated for patients whose cancers express HER2 (Human Epidermal growth factor Receptor 2) or have an amplified HER2 gene. HER2 is a protein found on the surface of some cancer cells that can promote their growth. This drug is being tested in patients with cancers that have progressed despite standard treatments. The trials are in early phases (Phase 1), meaning researchers are primarily looking at safety and determining the right dosage. It is not yet approved for use in colorectal cancer or any other cancer.

Mechanism of Action

A166 is being studied as a potential treatment for cancers expressing HER2. The specific way A166 works (its mechanism of action) is still being investigated in clinical trials. It is designed to target HER2-expressing cancer cells. The goal is to see if it can slow or stop the growth of these cancers.

Side Effects

Because A166 is an experimental drug in early-phase clinical trials The full range of potential side effects is still being evaluated. Side effects observed in the Phase 1 trial (NCT03602079) are being carefully monitored to determine the drug's safety profile and establish the maximum tolerated dose. Common side effects seen in early cancer drug trials can include fatigue Nausea Infusion reactions And changes in blood counts But specific data for A166 is still emerging.

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT05311397 Phase 1
Active, not recruiting
A Study of A166 in Patients With Advanced Solid Malignant Tumors
China
NCT03602079 Phase 1
Archived
Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
United States

Quick Info

CategoryOther Medications
EU EMA StatusExperimental
ES Spain AccessNot available
Clinical Trials2
View Clinical Trials Back to Drug Glossary

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Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult your healthcare team before making treatment decisions.