BMS-986490 (Not yet branded)

Other Medications

US Experimental IV 1 Clinical Trials
Not publicly disclosed

Description

BMS-986490 is an anti-cancer compound developed by Bristol Myers Squibb that is being evaluated in advanced solid tumors including colorectal cancer. This agent is designed to work either as monotherapy or in combination with bevacizumab, an anti-angiogenic therapy. Based on its development pattern and combination strategy, it appears to target specific molecular pathways involved in tumor growth and progression.

Mechanism of Action

The precise molecular mechanism of BMS-986490 has not been fully disclosed in public databases, though its pairing with bevacizumab suggests it may complement anti-angiogenic approaches. The compound likely targets specific proteins or signaling pathways that contribute to tumor cell survival, proliferation, or resistance mechanisms in solid tumors.

Molecular Targets

Side Effects

Data on specific side effects not yet publicly available from early-phase trials

Not all side effects are listed. Side effects vary by individual. Always consult your oncologist.

Clinical Trials

NCT06730750 med_phase_prefix1
Recruiting
A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors
United States, Australia, Canada