Volver a Ensayos Clínicos
NCT03365882
S1613: Trastuzumab y pertuzumab o cetuximab e hidrocloruro de irinotecán en el tratamiento de pacientes con cáncer colorrectal HER2/Neu amplificado, localmente avanzado o metastásico, que no puede ser tratado con cirugía.
Completado
Fase 2
Descripción
Este ensayo aleatorizado de fase II estudia la eficacia de trastuzumab y pertuzumab en comparación con cetuximab e irinotecán clorhidrato en el tratamiento de pacientes con cáncer colorrectal HER2/neu amplificado que se ha extendido desde su lugar de origen a otras partes del cuerpo y que no puede ser eliminado mediante cirugía. Los anticuerpos monoclonales, como trastuzumab y pertuzumab, pueden interferir con la capacidad de las células tumorales para crecer y diseminarse. Los fármacos utilizados en la quimioterapia, como cetuximab e irinotecán clorhidrato, actúan de diferentes maneras para detener el crecimiento de las células tumorales, ya sea matando las células, impidiendo que se dividan o impidiendo que se diseminen. La administración de trastuzumab y pertuzumab podría ser más eficaz en comparación con cetuximab e irinotecán clorhidrato en el tratamiento de pacientes con cáncer colorrectal.
Evidencia de la diana molecular en cáncer colorrectal
Estos fármacos NO son el fármaco de este ensayo. Es la eficacia publicada de OTROS fármacos que atacan la misma diana molecular, mostrada como contexto — no se refiere a este ensayo concreto ni confirma elegibilidad. Revísalo siempre con tu oncólogo.
Aún no hay evidencia documentada en nuestra base para la diana o el fármaco de este ensayo. Esta sección crece a medida que se procesan nuevas publicaciones.
Criterios de Elegibilidad
Criterios de inclusión:
- PASO 1: REGISTRO INICIAL: PRUEBA DE HER2
- Los pacientes deben tener adenocarcinoma de colon o recto histológicamente o citológicamente confirmado, que sea metastásico o localmente avanzado e irresecable.
- Resultados de las pruebas de mutación:
- Todos los pacientes deben someterse a pruebas moleculares en un laboratorio certificado por la Ley de Mejora de los Laboratorios Clínicos (CLIA), que incluya los genes KRAS y NRAS y el exón 15 del gen BRAF (mutación BRAF V600E); los pacientes con cualquier mutación activadora conocida en el exón 2 (codones 12 y 13), el exón 3 (codones 59 y 61) y el exón 4 (codones 117 y 146) de los genes KRAS/NRAS y en el exón 15 (mutación BRAFV600E) del gen BRAF no son elegibles.
- Los pacientes no deben haber recibido ninguno de los siguientes tratamientos antes del paso 1, registro inicial:
- Cetuximab, panitumumab o cualquier otro anticuerpo monoclonal contra EGFR o inhibidor de EGFR.
- Terapia dirigida a HER-2 para el tratamiento del cáncer colorrectal; los pacientes que hayan recibido previamente trastuzumab o pertuzumab para otras indicaciones, como antecedentes de tratamiento adyuvante o neoadyuvante para el cáncer de mama, son elegibles.
- Los pacientes no deben tener antecedentes de toxicidad grave e intolerancia o hipersensibilidad a irinotecán o cualquier otro fármaco del estudio; los pacientes no deben haber presentado una reacción grave relacionada con la infusión durante cualquier terapia previa con pertuzumab o trastuzumab.
- Los pacientes deben tener disponibles muestras de tumor para su envío para la prueba de HER-2; la prueba de HER-2 debe completarse por el laboratorio central antes del paso 2, aleatorización.
- Los pacientes deben estar informados de la naturaleza investigacional de este estudio y deben firmar y dar su consentimiento informado de acuerdo con las directrices institucionales y federales; para el paso 1, registro inicial, el formulario de consentimiento adecuado es el formulario de consentimiento del paso 1.
- Como parte del proceso de registro OPEN, se proporciona la identidad de la institución tratante para garantizar que la fecha actual (dentro de los 365 días) de la aprobación del comité de revisión institucional para este estudio se haya ingresado en el sistema.
- PASO 2: ALEATORIZACIÓN
- Los pacientes deben tener amplificación de HER-2, según lo determinado por las pruebas centrales (3+ o 2+ mediante inmunohistoquímica y amplificación del gen HER-2 mediante hibridación in situ con una relación de señales del gen HER-2 a señales del centrómero 17 >= 2.0).
- Los pacientes deben tener enfermedad medible que sea metastásica o localmente avanzada e irresecable; las imágenes utilizadas para evaluar toda la enfermedad según RECIST 1.1 deben haberse completado dentro de los 28 días anteriores al paso 2, aleatorización; toda la enfermedad debe evaluarse y documentarse en el Formulario de Evaluación del Tumor de la Línea de Base.
- Los pacientes deben haber recibido al menos un régimen previo de quimioterapia sistémica para enfermedad metastásica o localmente avanzada e irresecable; los pacientes deben haber presentado progresión después de la terapia más reciente; se permite el tratamiento previo con irinotecán; para los pacientes que recibieron quimioterapia adyuvante: no se requiere tratamiento previo para la enfermedad metastásica para los pacientes que experimentaron recurrencia de la enfermedad durante o dentro de los 6 meses posteriores a la finalización de la quimioterapia adyuvante; si el paciente recibió una línea de tratamiento adyuvante y tuvo recurrencia de la enfermedad después de 6 meses de completar la quimioterapia, los pacientes solo serán elegibles después de que haya fallado una línea adicional de quimioterapia utilizada para tratar la enfermedad metastásica o localmente avanzada e irresecable; los pacientes que hayan recibido >= 3 líneas de quimioterapia sistémica para enfermedad metastásica o localmente avanzada e irresecable no son elegibles.
- Los pacientes deben haber completado la quimioterapia, inmunoterapia o radioterapia previa al menos 14 días antes del paso 2, aleatorización, y toda la toxicidad debe haberse resuelto hasta el grado 1 de la versión (v) 4.0 de los Criterios de Terminología Común para los Eventos Adversos (CTCAE) (con la excepción de la neuropatía de grado 2 de CTCAE v4.0) antes del paso 2, aleatorización.
- Se permiten las metástasis cerebrales si han sido tratadas adecuadamente con radioterapia o cirugía y han estado estables durante al menos 30 días antes del paso 2, aleatorización; los pacientes elegibles deben estar neurológicamente asintomáticos y sin tratamiento con corticosteroides durante al menos 7 días antes del paso 2, aleatorización.
- Los pacientes deben tener un estado funcional de Zubrod de 0 o 1.
- Los pacientes deben tener un examen físico completo y un historial médico dentro de los 28 días anteriores al paso 2, aleatorización.
- Recuento absoluto de neutrófilos (RAN) >= 1500/mcL.
- Plaquetas >= 75.000/mcL.
- Hemoglobina >= 9 g/dL.
- Aspartato aminotransferasa (AST) y alanina aminotransferasa (ALT) ambas <= 5 veces el límite superior normal institucional (LSI).
- Bilirrubina <= 1,5 mg/dL.
- Depuración de creatinina calculada > 30 ml/min dentro de los 14 días anteriores al paso 2, aleatorización.
- Los pacientes que se hayan realizado una ecocardiografía dentro de los 6 meses anteriores al paso 2, aleatorización, deben tener una fracción de eyección ventricular (fracción de eyección ventricular izquierda [FEVI]) >= 50% o >= dentro de los límites normales para la institución.
- Los pacientes no deben tener una enfermedad intercurrente no controlada, que incluya, entre otras, diabetes, hipertensión, infección grave, desnutrición grave, angina inestable, insuficiencia cardíaca congestiva de clase III-IV de la Asociación Cardíaca de Nueva York (NYHA), arritmias ventriculares, enfermedad cardíaca isquémica activa o infarto de miocardio dentro de los 6 meses anteriores al paso 2, aleatorización.
- Los pacientes no deben tener ninguna condición previa o concurrente conocida que sugiera susceptibilidad a la hipersensibilidad o reacciones alérgicas, que incluya, entre otras: hipersensibilidad conocida a cualquiera de los tratamientos del estudio o a los excipientes de anticuerpos humanos o humanizados recombinantes; los pacientes con alergias leves o estacionales pueden incluirse después de discutirlo con los investigadores principales.
- Los pacientes no deben tener previsto recibir tratamiento con otros agentes anticancerígenos sistémicos (por ejemplo, quimioterapia, terapia hormonal, inmunoterapia) u otros tratamientos que no formen parte de la terapia anticancerígena especificada en el protocolo, incluidos los agentes investigacionales concurrentes de cualquier tipo.
- No se permite ninguna neoplasia maligna previa, excepto el cáncer de piel de células basales o de células escamosas tratado adecuadamente, el cáncer cervical in situ, el carcinoma ductal in situ u otras lesiones de bajo grado, como el carcinoide apendicular incidental, o cualquier otro cáncer del que el paciente haya estado libre de enfermedad y tratamiento durante dos años; los pacientes con cáncer de próstata en vigilancia activa son elegibles.
- Los pacientes no deben estar embarazadas ni amamantando; las mujeres en edad fértil deben tener una prueba de embarazo en suero negativa dentro de los 7 días anteriores al registro; las mujeres/hombres con potencial reproductivo deben haber aceptado utilizar un método anticonceptivo eficaz durante el estudio y durante al menos 7 meses después de la última dosis del tratamiento del estudio; se considera que una mujer tiene "potencial reproductivo" si ha tenido menstruación en cualquier momento durante los 12 meses consecutivos anteriores; además de los métodos anticonceptivos de rutina, "anticoncepción eficaz" también incluye la abstinencia sexual y la cirugía destinada a prevenir el embarazo (o con el efecto secundario de la prevención del embarazo), definida como histerectomía, ooforectomía bilateral o ligadura de trompas bilateral; sin embargo, si en algún momento un paciente que previamente se abstuvo sexualmente decide tener relaciones sexuales durante el período de tiempo para el uso de medidas anticonceptivas descritas en el protocolo, deberá comenzar a utilizar medidas anticonceptivas.
- Se debe dar a los pacientes la oportunidad de dar su consentimiento para la presentación opcional de tejido para futuras investigaciones.
- Los pacientes deben estar informados de la naturaleza investigacional de este estudio y deben firmar y dar su consentimiento informado por escrito de acuerdo con las directrices institucionales y federales; el formulario de consentimiento adecuado para este registro es el formulario de consentimiento del paso 2.
- PASO 2: ALEATORIZACIÓN: Como parte del proceso de registro de la Red de Inscripción de Pacientes Oncológicos (OPEN), se proporciona la identidad de la institución tratante para garantizar que la fecha actual (dentro de los 365 días) de la aprobación del comité de revisión institucional para este estudio se haya ingresado en el sistema.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Los pacientes deben tener progresión de la enfermedad documentada mientras están en CETIRI (Brazo 2) en este protocolo; el Formulario de Evaluación del Tumor de Seguimiento que documente la progresión de la enfermedad debe enviarse a Southwest Oncology Group (SWOG) antes del paso 3, registro de inclusión cruzada; el registro para el paso 3, inclusión cruzada, debe realizarse dentro de los 28 días posteriores a la interrupción del tratamiento con el protocolo CETIRI; los pacientes que interrumpan el tratamiento por cualquier otra razón no son elegibles.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Los pacientes deben tener un estado funcional de Zubrod de 0 o 1.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): RAN >= 1500/mcL.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Plaquetas >= 75.000/mcL.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Hemoglobina >= 9 g/dL.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): AST y ALT ambas <= 5 veces el límite superior normal institucional (LSI).
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Bilirrubina <= 1,5 mg/dL.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Depuración de creatinina calculada > 30 ml/min dentro de los 14 días anteriores al paso 3, registro de inclusión cruzada.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Los pacientes deben tener una fracción de eyección ventricular izquierda (FEVI) >= 50% o >= el límite inferior normal para la institución mediante ecocardiografía dentro de los 14 días anteriores al paso 3, registro de inclusión cruzada.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Los pacientes deben tener un magnesio, potasio, calcio, sodio, bicarbonato y cloruro determinados dentro de los 14 días anteriores al paso 3, registro de inclusión cruzada.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Los pacientes deben estar informados de la naturaleza investigacional de este estudio y deben firmar y dar su consentimiento informado por escrito de acuerdo con las directrices institucionales y federales; el formulario de consentimiento adecuado para este registro es el formulario de consentimiento del paso 2.
- PASO 3: REGISTRO DE INCLUSIÓN CRUZADA (OPCIONAL): Como parte del proceso de registro OPEN, se proporciona la identidad de la institución tratante para garantizar que la fecha actual (dentro de los 365 días) de la aprobación del comité de revisión institucional para este estudio se haya ingresado en el sistema.
Información del Ensayo
NCT03365882
Completado
Fase 2
240 participantes
Nov 2017
Nov 2022
Ubicaciones798
Puerto Rico (12)
Advance Oncology Center
Aguadilla
Doctor's Cancer Center-Arecibo
Arecibo
Cancer Center-Metro Medical Center Bayamon
Bayamón
Hematologia Oncologia San Pablo
Bayamón
HIMA San Pablo Oncologic Hospital
Caguas
Doctors Cancer Center
Manatí
Instituto Oncologia Moderna Ponce
Ponce
Centro Comprensivo de Cancer de UPR
San Juan
Primary Care Physician Group
San Juan
San Juan City Hospital
San Juan
San Juan Community Oncology Group
San Juan
Centro de Hematologia y Oncologia del Sur
Santa Isabel
United States (786)
Hawaii Cancer Care - Savio
‘Aiea
Pali Momi Medical Center
‘Aiea
Queen's Cancer Center - Pearlridge
‘Aiea
The Cancer Center of Hawaii-Pali Momi
‘Aiea
Providence Regional Cancer System-Aberdeen
Aberdeen
Hickman Cancer Center
Adrian
Riverwood Healthcare Center
Aitkin
Cleveland Clinic Akron General
Akron
Atrium Health Stanly/LCI-Albemarle
Albemarle
Lovelace Medical Center-Saint Joseph Square
Albuquerque
New Mexico Cancer Care Alliance
Albuquerque
New Mexico Oncology Hematology Consultants
Albuquerque
Presbyterian Kaseman Hospital
Albuquerque
University of New Mexico Cancer Center
Albuquerque
Lehigh Valley Hospital-Cedar Crest
Allentown
Saint Anthony's Health
Alton
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork
Community Hospital of Anaconda
Anaconda
Kaiser Permanente-Anaheim
Anaheim
Alaska Breast Care and Surgery LLC
Anchorage
Alaska Oncology and Hematology LLC
Anchorage
Alaska Women's Cancer Care
Anchorage
Anchorage Associates in Radiation Medicine
Anchorage
Anchorage Oncology Centre
Anchorage
Anchorage Radiation Therapy Center
Anchorage
Katmai Oncology Group
Anchorage
Providence Alaska Medical Center
Anchorage
Saint Joseph Mercy Hospital
Ann Arbor
University of Michigan Comprehensive Cancer Center
Ann Arbor
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande
PCR Oncology
Arroyo Grande
AdventHealth Infusion Center Asheville
Asheville
Duluth Clinic Ashland
Ashland
Northwest Wisconsin Cancer Center
Ashland
MultiCare Auburn Medical Center
Auburn
Sutter Auburn Faith Hospital
Auburn
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn
Children's Hospital Colorado
Aurora
Rocky Mountain Cancer Centers-Aurora
Aurora
Rush - Copley Medical Center
Aurora
The Medical Center of Aurora
Aurora
University of Colorado Hospital
Aurora
Mount Sinai Comprehensive Cancer Center at Aventura
Aventura
Saint Alphonsus Medical Center-Baker City
Baker City
Kaiser Permanente-Baldwin Park
Baldwin Park
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin
University of Maryland/Greenebaum Cancer Center
Baltimore
Flaget Memorial Hospital
Bardstown
Medical Center of Baton Rouge
Baton Rouge
Ochsner Health Center-Summa
Baton Rouge
Ochsner High Grove
Baton Rouge
Bronson Battle Creek
Battle Creek
McLaren Cancer Institute-Bay City
Bay City
Houston Methodist San Jacinto Hospital
Baytown
Indu and Raj Soin Medical Center
Beavercreek
Overlake Medical Center
Bellevue
Kaiser Permanente-Bellflower
Bellflower
PeaceHealth Saint Joseph Medical Center
Bellingham
Strecker Cancer Center-Belpre
Belpre
Saint Charles Health System
Bend
Alta Bates Summit Medical Center-Herrick Campus
Berkeley
Lehigh Valley Hospital - Muhlenberg
Bethlehem
Beverly Hospital
Beverly
Billings Clinic Cancer Center
Billings
Saint Vincent Frontier Cancer Center
Billings
Saint Vincent Healthcare
Billings
McLaren Cancer Institute-Bloomfield
Bloomfield
Illinois CancerCare-Bloomington
Bloomington
Saint Joseph's/Candler - Bluffton Campus
Bluffton
Saint Elizabeth Boardman Hospital
Boardman
Saint Alphonsus Cancer Care Center-Boise
Boise
Saint Luke's Cancer Institute - Boise
Boise
Central Care Cancer Center - Bolivar
Bolivar
Parkland Health Center-Bonne Terre
Bonne Terre
Boulder Community Foothills Hospital
Boulder
Boulder Community Hospital
Boulder
Rocky Mountain Cancer Centers-Boulder
Boulder
Bozeman Deaconess Hospital
Bozeman
Essentia Health Saint Joseph's Medical Center
Brainerd
Cox Cancer Center Branson
Branson
Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton
Harrison Medical Center
Bremerton
United Hospital Center
Bridgeport
IHA Hematology Oncology Consultants-Brighton
Brighton
Saint Joseph Mercy Brighton
Brighton
Henry Ford Cancer Institute-Downriver
Brownstown
Saint Joseph Regional Cancer Center
Bryan
Bryn Mawr Hospital
Bryn Mawr
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank
Highline Medical Center-Main Campus
Burien
Mills-Peninsula Medical Center
Burlingame
Lahey Hospital and Medical Center
Burlington
Fairview Ridges Hospital
Burnsville
Minnesota Oncology - Burnsville
Burnsville
Loyola Center for Health at Burr Ridge
Burr Ridge
Saint James Community Hospital and Cancer Treatment Center
Butte
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell
Cambridge Medical Center
Cambridge
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park
IHA Hematology Oncology Consultants-Canton
Canton
Illinois CancerCare-Canton
Canton
Saint Joseph Mercy Canton
Canton
Saint Francis Medical Center
Cape Girardeau
Southeast Cancer Center
Cape Girardeau
AtlantiCare Health Park-Cape May Court House
Cape May Court House
Memorial Hospital of Carbondale
Carbondale
Caro Cancer Center
Caro
Saint Anthony Regional Hospital
Carroll
Carson Tahoe Regional Medical Center
Carson City
SIH Cancer Institute
Carterville
Illinois CancerCare-Carthage
Carthage
Eden Hospital Medical Center
Castro Valley
Sandra L Maxwell Cancer Center
Cedar City
Rocky Mountain Cancer Centers - Centennial
Centennial
Dayton Physicians LLC-Miami Valley South
Centerville
Miami Valley Hospital South
Centerville
Centralia Oncology Clinic
Centralia
Providence Regional Cancer System-Centralia
Centralia
Atrium Health Pineville/LCI-Pineville
Charlotte
Atrium Health University City/LCI-University
Charlotte
Carolinas Medical Center/Levine Cancer Institute
Charlotte
Levine Cancer Institute-Ballantyne
Charlotte
Levine Cancer Institute-SouthPark
Charlotte
Memorial Hospital
Chattanooga
IHA Hematology Oncology Consultants-Chelsea
Chelsea
Saint Joseph Mercy Chelsea
Chelsea
Cheyenne Regional Medical Center-West
Cheyenne
Northwestern University
Chicago
Adena Regional Medical Center
Chillicothe
Marshfield Clinic-Chippewa Center
Chippewa Falls
Bethesda North Hospital
Cincinnati
Good Samaritan Hospital - Cincinnati
Cincinnati
Oncology Hematology Care Inc-Kenwood
Cincinnati
TriHealth Cancer Institute-Anderson
Cincinnati
TriHealth Cancer Institute-Westside
Cincinnati
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters
Clackamas Radiation Oncology Center
Clackamas
Providence Cancer Institute Clackamas Clinic
Clackamas
Hematology Oncology Consultants-Clarkston
Clarkston
McLaren Cancer Institute-Clarkston
Clarkston
Newland Medical Associates-Clarkston
Clarkston
Southeastern Medical Oncology Center-Clinton
Clinton
Henry Ford Macomb Hospital-Clinton Township
Clinton Township
Medical Oncology and Hematology Associates-West Des Moines
Clive
Mercy Cancer Center-West Lakes
Clive
AdventHealth Infusion Center Haywood
Clyde
Billings Clinic-Cody
Cody
Kootenai Health - Coeur d'Alene
Coeur d'Alene
Coffeyville Regional Medical Center
Coffeyville
Main Line Health Center-Collegeville
Collegeville
Memorial Hospital North
Colorado Springs
Penrose-Saint Francis Healthcare
Colorado Springs
Rocky Mountain Cancer Centers-Penrose
Colorado Springs
UCHealth Memorial Hospital Central
Colorado Springs
Columbus Oncology and Hematology Associates Inc
Columbus
Doctors Hospital
Columbus
Grant Medical Center
Columbus
Mount Carmel East Hospital
Columbus
Mount Carmel Health Center West
Columbus
Ohio State University Comprehensive Cancer Center
Columbus
Riverside Methodist Hospital
Columbus
The Mark H Zangmeister Center
Columbus
Atrium Health Cabarrus/LCI-Concord
Concord
Mercy Hospital
Coon Rapids
Bay Area Hospital
Coos Bay
Baptist Health Corbin
Corbin
Commonwealth Cancer Center-Corbin
Corbin
City of Hope Corona
Corona
UC Irvine Health Cancer Center-Newport
Costa Mesa
Alegent Health Mercy Hospital
Council Bluffs
Heartland Oncology and Hematology LLP
Council Bluffs
Jennie Edmundson Memorial Hospital
Council Bluffs
Greater Regional Medical Center
Creston
Siteman Cancer Center at West County Hospital
Creve Coeur
Parkland Memorial Hospital
Dallas
UT Southwestern/Simmons Cancer Center-Dallas
Dallas
Carle on Vermilion
Danville
Geisinger Medical Center
Danville
Sutter Davis Hospital
Davis
Dayton Physician LLC-Miami Valley Hospital North
Dayton
Good Samaritan Hospital - Dayton
Dayton
Miami Valley Hospital
Dayton
Miami Valley Hospital North
Dayton
Beaumont Hospital - Dearborn
Dearborn
Henry Ford Medical Center-Fairlane
Dearborn
Cancer Care Specialists of Illinois - Decatur
Decatur
Decatur Memorial Hospital
Decatur
Essentia Health - Deer River Clinic
Deer River
Northwestern Medicine Cancer Center Kishwaukee
DeKalb
Delaware Health Center-Grady Cancer Center
Delaware
Delaware Radiation Oncology
Delaware
Grady Memorial Hospital
Delaware
Cancer Center of Colorado at Sloan's Lake
Denver
Colorado Blood Cancer Institute
Denver
Denver Health Medical Center
Denver
National Jewish Health-Main Campus
Denver
Porter Adventist Hospital
Denver
Presbyterian - Saint Lukes Medical Center - Health One
Denver
Rocky Mountain Cancer Centers-Midtown
Denver
Rocky Mountain Cancer Centers-Rose
Denver
Rose Medical Center
Denver
SCL Health Saint Joseph Hospital
Denver
The Women's Imaging Center
Denver
Smilow Cancer Hospital-Derby Care Center
Derby
Broadlawns Medical Center
Des Moines
Iowa Lutheran Hospital
Des Moines
Iowa Methodist Medical Center
Des Moines
Medical Oncology and Hematology Associates-Des Moines
Des Moines
Medical Oncology and Hematology Associates-Laurel
Des Moines
Mercy Medical Center - Des Moines
Des Moines
Ascension Saint John Hospital
Detroit
Henry Ford Hospital
Detroit
Wayne State University/Karmanos Cancer Institute
Detroit
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes
Illinois CancerCare-Dixon
Dixon
City of Hope Comprehensive Cancer Center
Duarte
Dublin Methodist Hospital
Dublin
Epic Care-Dublin
Dublin
Essentia Health Cancer Center
Duluth
Essentia Health Saint Mary's Medical Center
Duluth
Miller-Dwan Hospital
Duluth
Mercy Medical Center
Durango
Southwest Oncology PC
Durango
Great Lakes Cancer Management Specialists-Doctors Park
East China Township
Pocono Medical Center
East Stroudsburg
Marshfield Medical Center-EC Cancer Center
Eau Claire
Fairview Southdale Hospital
Edina
Swedish Cancer Institute-Edmonds
Edmonds
Carle Physician Group-Effingham
Effingham
Crossroads Cancer Center
Effingham
AtlantiCare Surgery Center
Egg Harbor
Bay Area Breast Surgeons Inc
Emeryville
Epic Care Partners in Cancer Care
Emeryville
Walter Knox Memorial Hospital
Emmett
Mountain Blue Cancer Care Center - Swedish
Englewood
Rocky Mountain Cancer Centers - Swedish
Englewood
Swedish Medical Center
Englewood
The Melanoma and Skin Cancer Institute
Englewood
Saint Elizabeth Hospital
Enumclaw
Illinois CancerCare-Eureka
Eureka
Providence Regional Cancer Partnership
Everett
Main Line Health Center-Exton
Exton
Fairbanks Memorial Hospital
Fairbanks
Smilow Cancer Hospital Care Center-Fairfield
Fairfield
University of Kansas Clinical Research Center
Fairway
Essentia Health Cancer Center-South University Clinic
Fargo
Farmington Health Center
Farmington
Parkland Health Center - Farmington
Farmington
Weisberg Cancer Treatment Center
Farmington Hills
Saint Francis Hospital
Federal Way
Lake Region Healthcare Corporation-Cancer Care
Fergus Falls
Armes Family Cancer Center
Findlay
Blanchard Valley Hospital
Findlay
Orion Cancer Care
Findlay
Genesee Cancer and Blood Disease Treatment Center
Flint
Genesee Hematology Oncology PC
Flint
Genesys Hurley Cancer Institute
Flint
Hurley Medical Center
Flint
Singh and Arora Hematology Oncology PC
Flint
Kaiser Permanente-Fontana
Fontana
Levine Cancer Institute - Rutherford
Forest City
Cancer Care and Hematology-Fort Collins
Fort Collins
Poudre Valley Hospital
Fort Collins
Trinity Regional Medical Center
Fort Dodge
Holy Cross Hospital
Fort Lauderdale
Lee Memorial Health System
Fort Myers
Regional Cancer Center-Lee Memorial Health System
Fort Myers
Mercy Hospital Fort Smith
Fort Smith
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth
Essentia Health - Fosston
Fosston
Atrium Medical Center-Middletown Regional Hospital
Franklin
Dayton Physicians LLC-Atrium
Franklin
Palo Alto Medical Foundation-Fremont
Fremont
Unity Hospital
Fridley
Saint Luke's Cancer Institute - Fruitland
Fruitland
Illinois CancerCare-Galesburg
Galesburg
Western Illinois Cancer Treatment Center
Galesburg
Central Care Cancer Center - Garden City
Garden City
CaroMont Regional Medical Center
Gastonia
Levine Cancer Institute-Gaston
Gastonia
Northwestern Medicine Cancer Center Delnor
Geneva
MultiCare Gig Harbor Medical Park
Gig Harbor
Smilow Cancer Hospital Care Center at Glastonbury
Glastonbury
Addison Gilbert Hospital
Gloucester
Mountain Blue Cancer Care Center
Golden
National Jewish Health-Western Hematology Oncology
Golden
Southeastern Medical Oncology Center-Goldsboro
Goldsboro
Wayne Memorial Hospital
Goldsboro
CTCA at Western Regional Medical Center
Goodyear
Altru Cancer Center
Grand Forks
CHI Health Saint Francis
Grand Island
Grand Valley Oncology
Grand Junction
Saint Mary's Hospital and Regional Medical Center
Grand Junction
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids
Mercy Health Saint Mary's
Grand Rapids
Spectrum Health at Butterworth Campus
Grand Rapids
Central Care Cancer Center - Great Bend
Great Bend
Benefis Healthcare- Sletten Cancer Institute
Great Falls
Great Falls Clinic
Great Falls
North Colorado Medical Center
Greeley
UCHealth Greeley Hospital
Greeley
Dayton Physicians LLC-Wayne
Greenville
Wayne Hospital
Greenville
Academic Hematology Oncology Specialists
Grosse Pointe Woods
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods
Michigan Breast Specialists-Grosse Pointe Woods
Grosse Pointe Woods
Mount Carmel Grove City Hospital
Grove City
Smilow Cancer Hospital Care Center - Guiford
Guilford
Kaiser Permanente - Harbor City
Harbor City
Smilow Cancer Hospital Care Center at Saint Francis
Hartford
HaysMed University of Kansas Health System
Hays
Geisinger Medical Center-Cancer Center Hazleton
Hazleton
Lehigh Valley Hospital-Hazleton
Hazleton
Saint Peter's Community Hospital
Helena
21st Century Oncology-Henderson
Henderson
Cancer and Blood Specialists-Henderson
Henderson
Comprehensive Cancer Centers of Nevada - Henderson
Henderson
Comprehensive Cancer Centers of Nevada-Horizon Ridge
Henderson
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson
Las Vegas Cancer Center-Henderson
Henderson
Las Vegas Urology - Green Valley
Henderson
Las Vegas Urology - Pebble
Henderson
OptumCare Cancer Care at Seven Hills
Henderson
Urology Specialists of Nevada - Green Valley
Henderson
AdventHealth Hendersonville
Hendersonville
Essentia Health Hibbing Clinic
Hibbing
UCHealth Highlands Ranch Hospital
Highlands Ranch
South Carolina Cancer Specialists PC
Hilton Head Island
Pulmonary Medicine Center of Chattanooga-Hixson
Hixson
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood
Loyola Medicine Homer Glen
Homer Glen
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu
Hawaii Cancer Care Inc-Liliha
Honolulu
Island Urology
Honolulu
Kapiolani Medical Center for Women and Children
Honolulu
Kuakini Medical Center
Honolulu
Queen's Cancer Cenrer - POB I
Honolulu
Queen's Cancer Center - Kuakini
Honolulu
Queen's Medical Center
Honolulu
Straub Clinic and Hospital
Honolulu
The Cancer Center of Hawaii-Liliha
Honolulu
University of Hawaii Cancer Center
Honolulu
CHI Saint Vincent Cancer Center Hot Springs
Hot Springs
Houston Methodist Hospital
Houston
M D Anderson Cancer Center
Houston
Methodist Willowbrook Hospital
Houston
Edwards Comprehensive Cancer Center
Huntington
Centerpoint Medical Center LLC
Independence
Community Cancer Center East
Indianapolis
Community Cancer Center North
Indianapolis
Community Cancer Center South
Indianapolis
Franciscan Health Indianapolis
Indianapolis
Kaiser Permanente-Irvine
Irvine
Swedish Cancer Institute-Issaquah
Issaquah
Allegiance Health
Jackson
Onslow Memorial Hospital
Jacksonville
Southeastern Medical Oncology Center-Jacksonville
Jacksonville
Essentia Health - Jamestown Clinic
Jamestown
Mercyhealth Hospital and Cancer Center - Janesville
Janesville
Capital Region Southwest Campus
Jefferson City
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro
Freeman Health System
Joplin
Mercy Hospital Joplin
Joplin
Borgess Medical Center
Kalamazoo
Bronson Methodist Hospital
Kalamazoo
West Michigan Cancer Center
Kalamazoo
Kalispell Regional Medical Center
Kalispell
Kansas City Veterans Affairs Medical Center
Kansas City
Research Medical Center
Kansas City
Truman Medical Centers
Kansas City
University of Kansas Cancer Center
Kansas City
University of Kansas Cancer Center - North
Kansas City
University of Kansas Cancer Center-West
Kansas City
CHI Health Good Samaritan
Kearney
Heartland Hematology and Oncology
Kearney
Vidant Oncology-Kenansville
Kenansville
Kadlec Clinic Hematology and Oncology
Kennewick
First Dayton Cancer Care
Kettering
Greater Dayton Cancer Center
Kettering
Kettering Medical Center
Kettering
Illinois CancerCare-Kewanee Clinic
Kewanee
Kingman Regional Medical Center
Kingman
Vidant Oncology-Kinston
Kinston
Community Howard Regional Health
Kokomo
Gundersen Lutheran Medical Center
La Crosse
Providence Regional Cancer System-Lacey
Lacey
Marshfield Clinic - Ladysmith Center
Ladysmith
Franciscan Saint Elizabeth Health - Lafayette East
Lafayette
Good Samaritan Medical Center
Lafayette
Northwestern Medicine Lake Forest Hospital
Lake Forest
Rocky Mountain Cancer Centers-Lakewood
Lakewood
Saint Anthony Hospital
Lakewood
Saint Clare Hospital
Lakewood
City of Hope Antelope Valley
Lancaster
Fairfield Medical Center
Lancaster
McLaren-Greater Lansing
Lansing
Mid-Michigan Physicians-Lansing
Lansing
Sparrow Hospital
Lansing
Memorial Medical Center - Las Cruces
Las Cruces
21st Century Oncology
Las Vegas
21st Century Oncology-Fort Apache
Las Vegas
21st Century Oncology-Vegas Tenaya
Las Vegas
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas
Ann M Wierman MD LTD
Las Vegas
Cancer and Blood Specialists-Shadow
Las Vegas
Cancer and Blood Specialists-Tenaya
Las Vegas
Cancer Therapy and Integrative Medicine
Las Vegas
Comprehensive Cancer Centers of Nevada
Las Vegas
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas
Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas
Desert West Surgery
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-San Martin
Las Vegas
HealthCare Partners Medical Group Oncology/Hematology-Tenaya
Las Vegas
Hope Cancer Care of Nevada
Las Vegas
Las Vegas Cancer Center-Medical Center
Las Vegas
Las Vegas Prostate Cancer Center
Las Vegas
Las Vegas Urology - Cathedral Rock
Las Vegas
Las Vegas Urology - Pecos
Las Vegas
Las Vegas Urology - Smoke Ranch
Las Vegas
Las Vegas Urology - Sunset
Las Vegas
OptumCare Cancer Care at Charleston
Las Vegas
OptumCare Cancer Care at Fort Apache
Las Vegas
OptumCare Cancer Care at MountainView
Las Vegas
Radiation Oncology Centers of Nevada Central
Las Vegas
Radiation Oncology Centers of Nevada Southeast
Las Vegas
Summerlin Hospital Medical Center
Las Vegas
Sunrise Hospital and Medical Center
Las Vegas
University Cancer Center
Las Vegas
University Medical Center of Southern Nevada
Las Vegas
Urology Specialists of Nevada - Central
Las Vegas
Urology Specialists of Nevada - Northwest
Las Vegas
Urology Specialists of Nevada - Southwest
Las Vegas
Lawrence Memorial Hospital
Lawrence
Cancer Centers of Southwest Oklahoma Research
Lawton
Dartmouth Hitchcock Medical Center
Lebanon
University of Kansas Cancer Center - Lee's Summit
Lee's Summit
Kansas Institute of Medicine Cancer and Blood Center
Lenexa
Minimally Invasive Surgery Hospital
Lenexa
Geisinger Medical Oncology-Lewisburg
Lewisburg
Lewistown Hospital
Lewistown
Baptist Health Lexington
Lexington
Saint Joseph Hospital East
Lexington
Saint Joseph Radiation Oncology Resource Center
Lexington
University of Kentucky/Markey Cancer Center
Lexington
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue
Saint Rita's Medical Center
Lima
Saint Elizabeth Regional Medical Center
Lincoln
Atrium Health Lincoln/LCI-Lincolnton
Lincolnton
Littleton Adventist Hospital
Littleton
Rocky Mountain Cancer Centers-Littleton
Littleton
Hope Cancer Clinic
Livonia
Saint Mary Mercy Hospital
Livonia
Logan Regional Hospital
Logan
Loma Linda University Medical Center
Loma Linda
Saint Joseph London
London
Rocky Mountain Cancer Centers-Sky Ridge
Lone Tree
Sky Ridge Medical Center
Lone Tree
Longmont United Hospital
Longmont
Rocky Mountain Cancer Centers-Longmont
Longmont
PeaceHealth Saint John Medical Center
Longview
Kaiser Permanente Los Angeles Medical Center
Los Angeles
Kaiser Permanente West Los Angeles
Los Angeles
Los Angeles County-USC Medical Center
Los Angeles
USC / Norris Comprehensive Cancer Center
Los Angeles
Baptist Health Louisville
Louisville
Jewish Hospital
Louisville
Jewish Hospital Medical Center Northeast
Louisville
Saints Mary and Elizabeth Hospital
Louisville
McKee Medical Center
Loveland
Medical Center of the Rockies
Loveland
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Macomb
Illinois CancerCare-Macomb
Macomb
Michigan Breast Specialists-Macomb Township
Macomb
Baptist Health Madisonville/Merle Mahr Cancer Center
Madisonville
Norris Cotton Cancer Center-Manchester
Manchester
OhioHealth Mansfield Hospital
Mansfield
Fairview Clinics and Surgery Center Maple Grove
Maple Grove
Minnesota Oncology Hematology PA-Maplewood
Maplewood
Saint John's Hospital - Healtheast
Maplewood
Marietta Memorial Hospital
Marietta
OhioHealth Marion General Hospital
Marion
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette
Marshfield Medical Center-Marshfield
Marshfield
Contra Costa Regional Medical Center
Martinez
WVUH-Berkely Medical Center
Martinsburg
Fremont - Rideout Cancer Center
Marysville
Carle Physician Group-Mattoon/Charleston
Mattoon
Toledo Clinic Cancer Centers-Maumee
Maumee
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Maumee
Loyola University Medical Center
Maywood
Riddle Memorial Hospital
Media
Marjorie Weinberg Cancer Center at Loyola-Gottlieb
Melrose Park
Idaho Urologic Institute-Meridian
Meridian
Saint Luke's Cancer Institute - Meridian
Meridian
Mount Sinai Medical Center
Miami Beach
Woodland Cancer Care Center
Michigan City
Middlesex Hospital
Middletown
Abbott-Northwestern Hospital
Minneapolis
Health Partners Inc
Minneapolis
Hennepin County Medical Center
Minneapolis
Marshfield Clinic-Minocqua Center
Minocqua
Memorial Regional Cancer Center Day Road
Mishawaka
City of Hope Mission Hills
Mission Hills
Community Medical Hospital
Missoula
Saint Patrick Hospital - Community Hospital
Missoula
Memorial Medical Center
Modesto
Atrium Health Union/LCI-Union
Monroe
Toledo Clinic Cancer Centers-Monroe
Monroe
Monticello Cancer Center
Monticello
Franciscan Health Mooresville
Mooresville
West Virginia University Healthcare
Morgantown
McLaren Cancer Institute-Macomb
Mount Clemens
McLaren Cancer Institute-Central Michigan
Mount Pleasant
Good Samaritan Regional Health Center
Mount Vernon
Knox Community Hospital
Mount Vernon
Palo Alto Medical Foundation-Camino Division
Mountain View
Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View
Inspira Medical Center Mullica Hill
Mullica Hill
Intermountain Medical Center
Murray
Mercy Health Mercy Campus
Muskegon
Saint Alphonsus Medical Center-Nampa
Nampa
Saint Luke's Cancer Institute - Nampa
Nampa
Norris Cotton Cancer Center-Nashua
Nashua
Baptist Health Floyd
New Albany
Rutgers Cancer Institute of New Jersey
New Brunswick
Smilow Cancer Center/Yale-New Haven Hospital
New Haven
Yale University
New Haven
Ochsner Medical Center Jefferson
New Orleans
Cancer Center of Western Wisconsin
New Richmond
New Ulm Medical Center
New Ulm
Licking Memorial Hospital
Newark
Newark Beth Israel Medical Center
Newark
Newark Radiation Oncology
Newark
Providence Newberg Medical Center
Newberg
Bryn Mawr Health Center
Newtown Square
Lakeland Hospital Niles
Niles
Yale-New Haven Hospital North Haven Medical Center
North Haven
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores
Sutter Cancer Research Consortium
Novato
Henry Ford Medical Center-Columbus
Novi
Cancer Care Center of O'Fallon
O'Fallon
Alta Bates Summit Medical Center - Summit Campus
Oakland
Bay Area Tumor Institute
Oakland
McKay-Dee Hospital Center
Ogden
Integris Cancer Institute of Oklahoma
Oklahoma City
Integris Southwest Medical Center
Oklahoma City
Mercy Hospital Oklahoma City
Oklahoma City
University of Oklahoma Health Sciences Center
Oklahoma City
Olathe Health Cancer Center
Olathe
Alegent Health Bergan Mercy Medical Center
Omaha
Alegent Health Immanuel Medical Center
Omaha
Alegent Health Lakeside Hospital
Omaha
Creighton University Medical Center
Omaha
Hematology and Oncology Consultants PC
Omaha
Nebraska Methodist Hospital
Omaha
Kaiser Permanente-Ontario
Ontario
Saint Alphonsus Medical Center-Ontario
Ontario
Memorial GYN Plus
Ooltewah
Smilow Cancer Hospital-Orange Care Center
Orange
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange
Illinois CancerCare-Ottawa Clinic
Ottawa
Menorah Medical Center
Overland Park
University of Kansas Cancer Center-Overland Park
Overland Park
Baptist Health Paducah
Paducah
Hope Cancer Care of Nevada-Pahrump
Pahrump
Palo Alto Medical Foundation Health Care
Palo Alto
Kaiser Permanente - Panorama City
Panorama City
Paoli Memorial Hospital
Paoli
Midlands Community Hospital
Papillion
Essentia Health - Park Rapids
Park Rapids
Parker Adventist Hospital
Parker
Rocky Mountain Cancer Centers-Parker
Parker
Camden Clark Medical Center
Parkersburg
Singing River Hospital
Pascagoula
Lahey Medical Center-Peabody
Peabody
Illinois CancerCare-Pekin
Pekin
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Pekin
Memorial Hospital West
Pembroke Pines
Illinois CancerCare-Peoria
Peoria
Methodist Medical Center of Illinois
Peoria
OSF Saint Francis Medical Center
Peoria
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria
Mercy Health Perrysburg Cancer Center
Perrysburg
Illinois CancerCare-Peru
Peru
Valley Radiation Oncology
Peru
McLaren Cancer Institute-Northern Michigan
Petoskey
Fox Chase Cancer Center
Philadelphia
Temple University Hospital
Philadelphia
Ascension Via Christi - Pittsburg
Pittsburg
21st Century Oncology-Pontiac
Pontiac
Hope Cancer Center
Pontiac
Newland Medical Associates-Pontiac
Pontiac
Saint Joseph Mercy Oakland
Pontiac
Huron Medical Center PC
Port Huron
Lake Huron Medical Center
Port Huron
McLaren-Port Huron
Port Huron
Jefferson Healthcare
Port Townsend
Providence Portland Medical Center
Portland
Providence Saint Vincent Medical Center
Portland
Southern Ohio Medical Center
Portsmouth
Kootenai Clinic Cancer Services - Post Falls
Post Falls
Pottstown Hospital
Pottstown
Geisinger Cancer Services-Pottsville
Pottsville
Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo
Fairview Northland Medical Center
Princeton
Illinois CancerCare-Princeton
Princeton
Utah Valley Regional Medical Center
Provo
Rocky Mountain Cancer Centers - Pueblo
Pueblo
Saint Mary Corwin Medical Center
Pueblo
MultiCare Good Samaritan Hospital
Puyallup
Saint Charles Health System-Redmond
Redmond
Spectrum Health Reed City Hospital
Reed City
Radiation Oncology Associates
Reno
Renown Regional Medical Center
Reno
Saint Mary's Regional Medical Center
Reno
Valley Medical Center
Renton
Marshfield Medical Center-Rice Lake
Rice Lake
UT Southwestern Clinical Center at Richardson/Plano
Richardson
Vidant Oncology-Richlands
Richlands
Reid Health
Richmond
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho
Kaiser Permanente-Riverside
Riverside
Riverton Hospital
Riverton
North Memorial Medical Health Center
Robbinsdale
Great Lakes Cancer Management Specialists-Rochester Hills
Rochester Hills
Levine Cancer Institute-Rock Hill
Rock Hill
Delbert Day Cancer Institute at PCRMC
Rolla
Mercy Clinic-Rolla-Cancer and Hematology
Rolla
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville
Sutter Roseville Medical Center
Roseville
Scott and White Healthcare Round Rock
Round Rock
Sutter Medical Center Sacramento
Sacramento
University of California Davis Comprehensive Cancer Center
Sacramento
Ascension Saint Mary's Hospital
Saginaw
Oncology Hematology Associates of Saginaw Valley PC
Saginaw
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud
Norris Cotton Cancer Center-North
Saint Johnsbury
Heartland Regional Medical Center
Saint Joseph
Lakeland Medical Center Saint Joseph
Saint Joseph
Marie Yeager Cancer Center
Saint Joseph
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park
Regions Hospital
Saint Paul
United Hospital
Saint Paul
Sainte Genevieve County Memorial Hospital
Sainte Genevieve
Salina Regional Health Center
Salina
Huntsman Cancer Institute/University of Utah
Salt Lake City
LDS Hospital
Salt Lake City
Utah Cancer Specialists-Salt Lake City
Salt Lake City
Kaiser Permanente-San Diego Mission
San Diego
Kaiser Permanente-San Diego Zion
San Diego
California Pacific Medical Center-Pacific Campus
San Francisco
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo
Kaiser Permanente-San Marcos
San Marcos
Mills Health Center
San Mateo
Kootenai Cancer Clinic
Sandpoint
Essentia Health Sandstone
Sandstone
City of Hope - Santa Clarita
Santa Clarita
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz
Mission Hope Medical Oncology - Santa Maria
Santa Maria
Sutter Pacific Medical Foundation
Santa Rosa
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah
Low Country Cancer Care
Savannah
Summit Cancer Care-Candler
Savannah
Community Medical Center
Scranton
Kaiser Permanente Washington
Seattle
Pacific Gynecology Specialists
Seattle
Swedish Medical Center-Ballard Campus
Seattle
Swedish Medical Center-Cherry Hill
Seattle
Swedish Medical Center-First Hill
Seattle
PeaceHealth United General Medical Center
Sedro-Woolley
Geisinger Medical Oncology-Selinsgrove
Selinsgrove
Saint Francis Regional Medical Center
Shakopee
Atrium Health Cleveland/LCI-Cleveland
Shelby
Henry Ford Macomb Health Center - Shelby Township
Shelby
Providence Regional Cancer System-Shelton
Shelton
Jewish Hospital Medical Center South
Shepherdsville
Welch Cancer Center
Sheridan
Johnston Memorial Hospital
Smithfield
Memorial Hospital of South Bend
South Bend
South Jordan Health Center
South Jordan
City of Hope South Pasadena
South Pasadena
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
Spokane
MultiCare Deaconess Cancer and Blood Specialty Center - North
Spokane
MultiCare Deaconess Cancer and Blood Specialty Center - Valley
Spokane Valley
CoxHealth South Hospital
Springfield
Memorial Medical Center
Springfield
Mercy Hospital Springfield
Springfield
Mercy Medical Center
Springfield
Southern Illinois University School of Medicine
Springfield
Springfield Clinic
Springfield
Springfield Regional Cancer Center
Springfield
Springfield Regional Medical Center
Springfield
Mercy Hospital Saint Louis
St Louis
Mercy Hospital South
St Louis
Missouri Baptist Medical Center
St Louis
Saint Louis Cancer and Breast Institute-South City
St Louis
Siteman Cancer Center at Christian Hospital
St Louis
Siteman Cancer Center-South County
St Louis
Washington University School of Medicine
St Louis
Dixie Medical Center Regional Cancer Center
St. George
Geisinger Medical Group
State College
Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights
Marshfield Clinic Stevens Point Center
Stevens Point
Lakeview Hospital
Stillwater
Houston Methodist Sugar Land Hospital
Sugar Land
Missouri Baptist Sullivan Hospital
Sullivan
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale
Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills
Southwest Illinois Health Services LLP
Swansea
Franciscan Research Center-Northwest Medical Plaza
Tacoma
Mary Bridge Children's Hospital and Health Center
Tacoma
MultiCare Tacoma General Hospital
Tacoma
Northwest Medical Specialties PLLC
Tacoma
Ascension Saint Joseph Hospital
Tawas City
Scott and White Memorial Hospital
Temple
Union Hospital
Terre Haute
National Jewish Health-Northern Hematology Oncology
Thornton
Rocky Mountain Cancer Centers-Thornton
Thornton
Mercy Health - Saint Anne Hospital
Toledo
Saint Vincent Mercy Medical Center
Toledo
Toledo Clinic Cancer Centers-Toledo
Toledo
University of Kansas Health System Saint Francis Campus
Topeka
Smilow Cancer Hospital-Torrington Care Center
Torrington
Munson Medical Center
Traverse City
Dayton Physicians LLC-Upper Valley
Troy
Upper Valley Medical Center
Troy
Smilow Cancer Hospital Care Center-Trumbull
Trumbull
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa
Saint Luke's Cancer Institute - Twin Falls
Twin Falls
City of Hope Upland
Upland
Carle Cancer Center
Urbana
The Carle Foundation Hospital
Urbana
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Vacaville
Sutter Solano Medical Center/Cancer Center
Vallejo
PeaceHealth Southwest Medical Center
Vancouver
Inspira Medical Center Vineland
Vineland
Essentia Health Virginia Clinic
Virginia
Ridgeview Medical Center
Waconia
Providence Saint Mary Regional Cancer Center
Walla Walla
Epic Care Cyberknife Center
Walnut Creek
Advanced Breast Care Center PLLC
Warren
Great Lakes Cancer Management Specialists-Macomb Professional Building
Warren
Macomb Hematology Oncology PC
Warren
Michigan Breast Specialists-Warren
Warren
Saint John Macomb-Oakland Hospital
Warren
Saint Joseph Warren Hospital
Warren
Northwestern Medicine Cancer Center Warrenville
Warrenville
Kent Hospital
Warwick
Illinois CancerCare - Washington
Washington
Mercy Hospital Washington
Washington
Smilow Cancer Hospital-Waterbury Care Center
Waterbury
Smilow Cancer Hospital Care Center - Waterford
Waterford
Marshfield Clinic-Wausau Center
Wausau
AdventHealth Infusion Center Weaverville
Weaverville
Henry Ford West Bloomfield Hospital
West Bloomfield
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch
City of Hope West Covina
West Covina
Mercy Medical Center-West Lakes
West Des Moines
Methodist West Hospital
West Des Moines
Reading Hospital
West Reading
Saint Ann's Hospital
Westerville
Marshfield Medical Center - Weston
Weston
University of Kansas Hospital-Westwood Cancer Center
Westwood
SCL Health Lutheran Medical Center
Wheat Ridge
Cancer Center of Kansas - Wichita
Wichita
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre
Rice Memorial Hospital
Willmar
Winchester Hospital
Winchester
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids
Minnesota Oncology Hematology PA-Woodbury
Woodbury
Kaiser Permanente-Woodland Hills
Woodland Hills
Lankenau Medical Center
Wynnewood
Fairview Lakes Medical Center
Wyoming
Metro Health Hospital
Wyoming
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima
Providence Regional Cancer System-Yelm
Yelm
Rush-Copley Healthcare Center
Yorkville
Saint Elizabeth Youngstown Hospital
Youngstown
Huron Gastroenterology PC
Ypsilanti
IHA Hematology Oncology Consultants-Ann Arbor
Ypsilanti
Genesis Healthcare System Cancer Care Center
Zanesville